Airborne transmission is considered one of the most common ways of transmitting respiratory viruses. The reach of airborne pathogens and persistence of aerosolized particles suspended in the air are a significant concern for the spread of pandemic and seasonal respiratory diseases. This is particularly relevant in indoor spaces where most respiratory infections occur. Controlling the transmission of airborne pathogens is therefore a cornerstone of public health efforts to manage and prevent the spread of infectious diseases, ensuring safety and health for individuals and communities. Technologies that allow such control are essential to address the challenge.

This report is the output of a comprehensive study which evaluates the potential of the current technology landscape for suppressing indoor airborne pathogen transmission. The analysis outlines two main technology groups: those for detecting airborne pathogens and those for decontaminating air and surfaces. It identifies several key technologies in each group, and assesses their maturity, impact, and potential priority for funding. It outlines the drivers, enablers, and barriers for the development and adoption of these technologies, providing insights into factors that may influence their future implementation. It also explores forward-looking perspectives with scenarios for future health crises and offers recommendations for policy and research to address the challenges and leverage the opportunities in the field of indoor air quality.

This is the final report from a foresight study that aimed at supporting the development of the Strategic Plan of Horizon Europe (2025-2027). The study lasted for 18 months and involved a wide range of activities that this report aims at presenting.

These activities aimed at providing early-stage strategic intelligence and sense-making contributions – issues, trends, perspectives, ideas - that could contribute novel elements to the more structured processes of strategic planning that were to follow. The work followed two important directions that were recommended by EFFLA (2012)1 as core elements of bringing foresight into EU R&I policy: knowledge-based review and broad engagement.

Knowledge based review was conducted with the help of the 40 experts who constituted the team that worked on the project. All these experts have contributed as authors to the authorship of the different chapters of this report. About 300 additional experts contributed to the project through its numerous workshops that helped shape the scenarios and ideas about their policy implications, and through membership in the on-line platform of the project at www.futures4europe.eu, which reached 307 people. Last, we acknowledge the 943 experts who responded to our final consultation survey on the implications of our foresight for the directions of EU R&I policy.

The foresight process
The foresight process in support of the 2nd Strategic Plan comprised a wide spectrum of activities:
• As a reference point for the exploratory work, the explicit and implicit impact assumptions of the 1st Strategic Plan were identified and visualised with the help of a qualitative system analysis and modelling tool for causal loop analysis.
• An exploratory analysis of forward-looking sources (e.g. foresight reports, web-based horizon scanning) was conducted to identify relevant trends and signals of unexpected developments. These were discussed in online workshops and on www.futures4europe.eu.
• An outlook on emerging developments in the global and European context of EU R&I policy was developed drawing on a major online workshop in autumn 2021 with some 60 participants, experts and policy makers, who worked with multi-level context scenarios and specific context narratives about emerging disruptions.
• On that basis and in close consultation with the European Commission involving another major workshop in February 2022 which brought together 80 participants, Expert Teams were set up to develop disruptive scenarios in five areas of major interest. Each team ran several internal workshops but also involved further experts and Commission staff in their work, both through the online platform and through a final policy-oriented workshop. The foresight work within the areas of interest resulted in five deep dives on the following topics:
> Climate change, Research, and Innovation: Radical Options from Social Change to Geoengineering
> Hydrogen Economy – A radical alternative
> The EU in a Volatile New World - The challenge of global leadership
> Global Commons
> Transhumanist Revolutions
• Further areas of interest identified since were explored through review papers aiming to capture major trends, developments and scenario sketches in relation to further disruptive developments
> Social Confrontations
> Artificial General Intelligence: Issues and Opportunities
> The Interpenetration of Criminal and Lawful Economic Activities
> The Future of Health
• A third major workshop took place in October 2022 bringing together all the thematic strands of work and addressing possible R&I policy implications from this work. Participation in this workshop reached 250 individuals over 2 days.
• Building on the workshop, the online Dynamic Argumentative Delphi survey Research4Futures collect suggestions from further experts and citizens about the implications of this foresight work for the priorities of EU R&I policy.

This foresight study has been the most widely engaging foresight exercise yet aiming to support EU R&I policy. Through this broad engagement, the study did not only develop intelligence for the 2nd Strategic Plan of Horizon Europe but also contributed to the development of an EU R&I foresight community, one that is an asset for future R&I policies across Europe. 

Results for the working group Health are available at: http://foresight.cnr.it/working-groups/wg-health.html

Airborne transmission is considered one of the most common ways of transmitting respiratory viruses. The reach of airborne pathogens and persistence of aerosolized particles suspended in the air are a significant concern for the spread of pandemic and seasonal respiratory diseases. This is particularly relevant in indoor spaces where most respiratory infections occur. 

Controlling the transmission of airborne pathogens is therefore a cornerstone of public health efforts to manage and prevent the spread of infectious diseases, ensuring safety and health for individuals and communities. Technologies that allow such control are essential to address the challenge. This report is the output of a comprehensive study which evaluates the potential of the current technology landscape for suppressing indoor airborne pathogen transmission. 

The analysis outlines two main technology groups: those for detecting airborne pathogens and those for decontaminating air and surfaces. It identifies several key technologies in each group, and assesses their maturity, impact, and potential priority for funding. It outlines the drivers, enablers, and barriers for the development and adoption of these technologies, providing insights into factors that may influence their future implementation. It also explores forward-looking perspectives with scenarios for future health crises and offers recommendations for policy and research to address the challenges and leverage the opportunities in the field of indoor air quality. 

The study was conducted during 2024 by European Commission Joint Research Centre (JRC) and Health Emergency Preparedness and Response Authority (HERA).

We’re pioneering the European Health Data Space by building the first Regional Smart Health Data Space.

On an Ambitious Mission
We embarked on an ambitious mission to reshape the smart healthcare landscape and accelerate innovation within four Widening countries – Bulgaria, Romania, Cyprus, and Greece.

Our overarching objective is to foster an environment where smart health innovations thrive, creating excellent innovation ecosystems within the participating widening countries, while having the support of three developed countries – Sweden, Germany, and Spain.

Aligned with the Regional Research and Innovation Strategies for Smart Specialisation (RIS3) in healthcare, we aim to leverage cutting-edge technologies such as Big Data, Artificial Intelligence (AI), and the Internet of Things (IoT) to enable personalized medicine, informed decision-making, and enhanced disease prediction.

Beacons of Innovation
We will create the first Regional Smart Health Data Space (RSHDS). This marks a significant milestone on our journey towards a unified European Health Data Space (EHDS).

We will showcase the capabilities of the RSHDS through the implementation of four interconnected pilots, each addressing critical healthcare challenges:

• Cancer treatment (Greece)
• Alzheimer (Bulgaria)
• Cerebral tumours (Romania)
• Dementia (Cyprus)

Within this project, UEFISCDI is leading, among other activities, Task 6.3 - Long term common R&I and investment strategic agenda and action plan. The task will develop a joint R&I strategic agenda aligned with regional/national Smart Specialization Strategies, with local and European regulations concerning data governance and data sharing, as well as with the European Policy priority of Data Driven Digital Transition and Smart Health.

For this, it will use foresight-based methodologies such as backcasting, visioning, foresight expert workshops and other. 

SF4S is a collaborative action with partners from Higher Education institutions (HEIs), Vocational Education and Training (VET) providers, innovation networks and business entities from the Agri-food, Health and the Mobility sectors.

Carried out between July 2022 - June 2025, SF4S supports our transition to a more sustainable European economy by helping to address the lack of green, digital and future (i.e. sustainability foresight) skills among students and professionals and by connecting knowledge flows between HEI, VET and industry actors that are necessary for Europe to develop cooperative solutions on a large-scale and support the recommendations for action in the major reports and initiatives: Green Deal, NextGenerationEU, European Skills Agenda and OECD Future of Education and Skills 2030.

This foresight study aimed at supporting the development of the Strategic Plan of Horizon Europe (2025-2027), by providing early-stage strategic intelligence and sense-making that could contribute novel elements to the processes of strategic planning.

The study, which was launched in mid-2021 and lasted almost two years, has been the most widely engaging foresight exercise yet aiming to support EU R&I policy. Through this broad engagement, the study did not only develop intelligence for the 2nd Strategic Plan of Horizon Europe but also contributed to the development of an EU R&I foresight community hosted by futures4europe.eu, one that is an asset for future R&I policies across Europe.

The foresight process in support of the 2nd Strategic Plan comprised a wide spectrum of activities:

• As a reference point for the exploratory work, the explicit and implicit impact assumptions of the 1st Strategic Plan were identified and visualised with the help of a qualitative system analysis and modelling tool for causal loop analysis.
• An exploratory analysis of forward-looking sources (e.g. foresight reports, web-based horizon scanning) was conducted to identify relevant trends and signals of unexpected developments. These were discussed in online workshops and on futures4europe.eu.
• An outlook on emerging developments in the global and European context of EU R&I policy was developed drawing on a major online workshop in autumn 2021 with some 60 participants, experts and policy makers, who worked with multi-level context scenarios and specific context narratives about emerging disruptions.
• On that basis and in close consultation with the European Commission involving another major workshop in February 2022 which brought together 80 participants, Expert Teams were set up to develop disruptive scenarios in five areas of major interest. Each team ran several internal workshops but also involved further experts and Commission staff in their work, both through the online platform and through a final policy-oriented workshop. The foresight work within the five areas of interest resulted in deep dives on the following topics:
  > Climate change, Research, and Innovation: Radical Options from Social Change to Geoengineering
  > Hydrogen Economy – A radical alternative
  > The EU in a Volatile New World - The challenge of global leadership
  > Global Commons
  > Transhumanist Revolutions
  
• Further areas of interest identified were explored through review papers aiming to capture major trends, developments and scenario sketches in relation to further disruptive developments:
  > Social Confrontations
  > Artificial General Intelligence: Issues and Opportunities
  > The Interpenetration of Criminal and Lawful Economic Activities
  > The Future of Health
  
• A third major workshop took place in October 2022 bringing together all the thematic strands of work and addressing possible R&I policy implications from this work. Participation in this workshop reached 250 individuals over 2 days.
• Building on the workshop, the online Dynamic Argumentative Delphi survey Research4Futures collected suggestions from almost 950 contributors from Europe and beyond about the implications of this foresight work for the priorities of EU R&I policy.

The detailed description of the foresight work and the resulting outputs are available in the final report of the project.

This foresight study has been implemented through the Foresight on Demand framework contract, by a team of 40 experts. About 300 additional experts contributed to the project through its numerous workshops that helped shape the scenarios and their policy implications. 

Nobody wants to die early. The desire to stay healthy and to have a long-lasting life is enormous. At first glance, it seems as if the increasing number of older people in the EU is in accordance with that. When having a closer look at that trend, three main factors seem to contribute to an overall older population: a generally increased life expectancy, a modern, readily accessible medical system, healthier lifestyles, and low birth rates. Migration is a counter-trend to the ageing society, as the majority of migrants to the EU are young families. This fact, however, does not substantially diminish the absolute number of older people in the EU. The potential consequences are diverse. Although people get older while being healthier, it is likely that the cost of health care will rise, putting an extra burden on the health insurance system. Hence, we might have to expect a clear social divide: Will only rich people be able to afford to get old? Or are the additional health-related costs going to be shifted to younger generations? Will the state have to step in?

Proposed scenarios about the future should come with a pinch of salt. Without being perfectly accurate, they help prepare policymakers for better or worse. The REGROUP project funded under the Horizon Europe programme aims to advise the EU on how to address post-pandemic policy and institutional challenges by analysing the societal and political consequences of COVID-19 and considering the normative implications of the pandemic.